Preimplantation Genetic Diagnosis (PGD) is an examination method that enables couples with genetic diseases in their families or for infertile couples who have not responded to the treatments to get a healthy baby using the IVF method.
In this technique, the embryos obtained from the couples are examined one by one and the genetically healthy embryos are separated from the abnormal embryos. The embryos that are determined to be genetically normal are then transferred to the mother candidate.
PGD has three main uses. The first one is for older women who are trying to become pregnant through IVF treatment. In particular, the percentage of oocytes containing chromosomal abnormalities increases at a certain rate from the age of 37, and abnormal embryos can be formed by fertilization of these eggs.
In older women who have an IVF, pregnancy rate increases and miscarriage rates are decreased by testing embryos with PGD and placing normal embryos in the uterus.
The second area of use of PGD is for couples that can not conceive in repetitive IVF applications. There is a possibility of abnormal embryos behind the recurrent IVF failures.
In this group of couples, abnormal embryos and normal embryos are identified and the pregnancy rates are increased by the transfer of genetically normal embryos.
The third use of PGD is for women who have had repeated miscarriages. PGD may be useful, especially if the reason of miscarriages are the pregnancies that are obtained by abnormal embryos.