Sperm donation is the utilization of another man’s sperms for the process of egg fertilization. Another man’s sperms can be used in cases when no sperm is available, when there is insufficient sperm being produced or in cases when the utilization of the sperm is objectionable due to diseases. In addition, sperm donation is a procedure that can be applied to single women.
For which patients is Sperm Donation recommended?
- Patients that have azoospermia (absence of sperm) and inability to obtain sperm through microTESE or TESE
- Patients who have had poor results in IVF treatment due to low sperm quality
- Patients who carry a genetic disease that makes it impossible to work on embryos
- Patients who have a viral disease which cannot be removed from the semen
- In cases when a serious chromosomal abnormality is detected in the sperm
- In cases when the man is Rh+ and an isoimmunisation is detected in the women’s previous pregnancy because of this.
- Single women
How are individuals chosen for sperm donation?
Sperm donors are chosen from a sperm bank. Each donor has a certificate for disease screening. The donor is chosen in accordance to the physical characteristics and blood type of the recipient.
Detailed research is carried out to detect chromosome analysis (karyotype), thalassemia, cystic fibrosis and infectious diseases (hepatitis B, hepatitis C, HIV, syphilis, CMV). There is also additional information provided regarding the sperm donor such as his profession, a photograph from his childhood and a sample of his handwriting.
How are preparations made?
A preliminary preparation method for the female is essential before the utilization of the sperm. For this, hormone medication is given to the patient following certain tests. This is called ovulation induction. The tests necessary for women are: Full blood count, blood type, PT, aPTT, HBsAg, AntiHCV, AntiHIV, VDRL, AntiRubella IgG, TSH, FT4, and Prolactin. Additionally, AMH, uterus x-ray (HSG) and chromosome analysis is requested from the woman in necessary cases. A pelvic ultrasound is necessary to be able to understand the female’s egg reserve and the patient’s treatment dosage is determined according to this.
The treatment is started on the 2nd or the 3rd day of menstruation. A hormone treatment is applied for approximately for 10-12 days with injections to the abdomen. A maturation injection is given after a certain number and size of eggs are reached and the eggs are collected 35-36 hours later under a mild sedation in our clinic (OPU procedure). The collected eggs and the sperm donor’s sperms are united (fertilisation) in a laboratory environment and the embryo developments are monitored. Embryos are transferred on the 3rd or 5th days. The transfer procedure is a painless 10 minutes procedure that doesn’t require anaesthesia.
The patients who can’t stay in Cyprus during the entire treatment period can start their treatments in the city they live in and can complete their preliminary preparations until the eggs are ready to be collected in our centre.
What is the success rate of sperm donation?
The main factors that affect the success rate of sperm donation are the woman’s age, the number of the eggs and the quality of the eggs. Due to the high quality of the sperm, the main determinant in a successful pregnancy is the characteristics of the recipient woman.